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Longevity

The Benefits Of Fasting: Part 2 – Slowing Ageing?

Posted on 27 November 2020

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What we currently know about the underlying mechanisms of ageing and the effects of fasting on these mechanisms suggests that fasting should slow the ageing process. There is also solid evidence that fasting improves some of the markers associated with ageing, but to conclude that fasting actually slows ageing down will require more robust human evidence. Perhaps getting hung up on ageing itself is missing half the point, though. Even if fasting doesn’t make you biologically younger, it will help you live a longer, healthier life free from chronic diseases of ageing.


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    References

    Influence of short-term repeated fasting on the longevity of female (NZB x NZW)F1 mice: DOI: 10.1016/s0047-6374(00)00109-3

    Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans: https://doi.org/10.1038/nature07583

    Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension: DOI: 10.1016/j.cub.2018.04.015

    Effects of intermittent feeding upon growth and life span in rats: DOI: 10.1159/000212538

    Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians: DOI: 10.1016/j.stemcr.2019.06.005

    Time-controlled fasting prevents aging-like mitochondrial changes induced by persistent dietary fat overload in skeletal muscle: doi: 10.1371/journal.pone.0195912

    Dietary Restriction, Growth Factors and Aging: from yeast to humans: doi: 10.1126/science.1172539

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