Posted on 12 May 2019
Researchers have created a publicly available catalogue containing 56,592 different protein mutations present in colon-cancer tissue, which could unearth important biomarkers to help doctors characterise different types of colon cancer.
The analysis also flagged genes that were unusually active in cancerous tissue, including some that are known to have a role in tumour suppression. A reaction called phosphorylation helped to account for the elevated activity, so the authors suggest that curbing the reaction might return the proteins to their usual anti-cancer function.Source: nature.com
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