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E. senticosus May Protect Against Fatigue and The Effects Of Stress

Posted on 25 August 2020

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Eleutherococcus senticosus, also known as Siberian ginseng, is a species of small, woody shrub native to Northeastern Asia. It is thought to be an adaptogen: a molecule that increases resistance against the physical and chemical effects of stress.

Why Might Eleutherococcus Senticosus Be Beneficial?

Stress is associated with more rapid age-related decline, including increased inflammation and reduced immune function, which in turn increases the risk of developing age-related chronic diseases. Furthermore, our ability to resist the physiological effects of stress declines as we age.

Adaptogens such as E. senticosus may be protective against the effects of stress, thereby slowing cognitive decline, boosting the immune system and protecting against DNA damage. E. senticosus may also relieve stress-induced fatigue and improve exercise performance.

What Is The Evidence Behind Eleutherococcus Senticosus Supplementation?

Most of the evidence concerning E. senticosus is preliminary, with more research needed to draw firm conclusions about its benefits. Two studies point to an increase in the population of immune cells (specifically T cells and natural killer cells) with supplementation, but it is unknown whether this translates to protection against infectious diseases.

One randomised, double-blind placebo-controlled trial found an improvement in cognitive function among elderly hypertensives who took E. senticosus. However, this benefit faded with continued use.

Some studies suggest that E. senticosus improves fatigue resistance and aerobic running capacity, but unfortunately is not very reliable in doing so.

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      Eleutherococcus senticosus:

      Effect of Eleutherococcus senticosus extract on human physical working capacity: doi: 10.1123/ijsnem.15.1.75.

      The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human: doi: 10.4077/cjp.2010.amk018.

      Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial: DOI: 10.1016/j.archger.2004.04.012

      Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent:

      The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man: DOI: 10.1002/(sici)1099-1573(200002)14:1<30::aid-ptr543>;2-m

      The effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal women: DOI: 10.1016/j.bbrc.2008.07.097

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