Posted on 23 March 2020
The WHO has announced a global trial, called SOLIDARITY, to assess the effectiveness of the four most promising coronavirus treatments currently under investigation:
Confirmed cases of COVID-19 who are eligible can enrol to receive one of the drugs at random. The trial will not be double blind, as the trial seeks to balance scientific rigour with speed. The WHO are also seeking to keep the trial as simple as possible, so that hospitals struggling under a heavy burden of cases can still contribute.
The design of the trial will remain flexible – some drugs may be dropped once they prove to be ineffective, while new drugs could be included.
WHO launches global megatrial of the four most promising coronavirus treatments: https://www.sciencemag.org/news/2020/03/who-launches-global-megatrial-four-most-promising-coronavirus-treatments