The Methuselahs – Longest Lived Organisms With And Without Interventions
During the last 25 years, by targeting the underlying processes of aging biomedical scientists have been able to improve the health and lifespan of model organisms, from worms and flies, to rodents and fish. We can now consistently improve the lifespan of C. elegans by more than 10 fold, more than double the lifespan of flies and mice, and improve the lifespan of rats and killifish by 30% and 59%, respectively (see figure)
Currently, our treatment options for the underlying processes of aging in humans are limited. However, with current progress in the development of geroprotective drugs, regenerative medicine, and precision medicine interventions, we will soon have the potential to slow down aging.
To find our more about this topic please read our latest paper in Frontiers of Genetics, titled “It is time to classify biological aging as a disease