Scientists capture images of CRISPR/Cas9 in action

Using cryo-EM, researchers have captured three-dimensional images of how the major domains of CRISPR-Cas9 moves and interacts during and after DNA cleavage.

These images provide us with invaluable information to improve the efficiency of the gene-editing process so that we can hopefully correct disease-causing DNA mutations more quickly and precisely in the future.

UBC researcher Sriram Subramaniam, who led the cryo-EM studies.