Longevity Briefs: The drugs that reverse human ageing

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Longevity briefs provides a short summary of novel research in biology, medicine, or biotechnology that caught the attention of our researchers in Oxford, due to its potential to improve our health, wellbeing, and longevity.

Dr. Fahy is a world renowned cryobiologist and is also the chief science officer, and co-founder, of Intervene Immune, a company which pioneers treatments for thymus regeneration and age-related immune system decline.. In this short extract from Chris’s discussion with Dr. Fahy, he talks about the Thymic Rejuvenation, Immunorestoration and Insulin Mitigation (TRIIM) trial, which revealed that a cocktail of DHEA, metformin and growth hormone could reverse ageing in humans.

In thw full talk, Dr. Fahy discusses the results from his personal long-term health journey, his current work, and how he plans to improve human health and longevity.

Using evidence from the TRIIM trial, Dr. Fahy’s company Intervene Immune, Inc. is expanding this pilot study to a Phase 2 clinical trial where he will be enrolling 85 participants between 40 and 80 years old. The clinical trial is called the Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X), and it aims to use a personalised combination of somatropin, metformin, and DHEA to regrow the participant’s thymus.

Watch the full conversation talk with Greg.