Physiology

Injectable Foam To Treat Bone Degeneration

Posted on 15 January 2016

Credit: German Tenorio/Flickr

Credit: German Tenorio/Flickr

70% of bone is made of hydroxyapatite – a calcium phosphate mineral. This is what has allowed calcium phosphate cement (CPC) to be used as a bone substitute in surgery for almost 100 years. The reason this hasn’t yet been used to treat degenerative diseases is because we didn’t know how to make the cement with pores larger than 50 nanometers – i.e. “macroporous”.

Credit: Gizmodo

Credit: Gizmodo

By preparing the CPC with Si-HPMC solution (a silanized hydrogel foaming agent) and air, French scientists at the University of Nantes were able to create an injectable, self-setting, macroporous calcium phosphate foam that has the potential to treat degenerative diseases such as osteoporosis.

Read more at Gizmodo and ScienceDirect


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