Posted on 9 March 2020
We literally have the potential to take people who are essentially blind and make them seeCharles Albright, the chief scientific officer at Editas Medicine
In an hour long procedure, undertaken at the Oregon Casey Eye Institute, three drops of fluid, containing genetically engineered viral vector, were injected into a patients eye, with the hope to restore the individuals sight.
This gene editing procedure was aiming to knockout the CEP290 gene, thought to cause Leber congenital amaurosis. This is a rare, and previously incurable, genetic eye disorder causing blindness of the victim from birth.
One of the major benefits of this gene therapy is that if it is successful, it is permanent, the corrected cells will persist for life.
Although gene editing tools have been used in the body before, CRISPR is a much simpler tool for locating and cutting DNA at a particular site, with some scientists lauding this as “a new era in medicine”.
There are currently 18 other patients lined up for a similar procedure if the first procedure is deemed a success after a waiting period.
OHSU performs first-ever CRISPR gene editing within human body. https://news.ohsu.edu/2020/03/04/ohsu-performs-first-ever-crispr-gene-editing-within-human-body
Doctors try 1st CRISPR editing in the body for blindness. https://www.newser.com/article/a9cc5e5590ada54ce189c66677b3eee4/doctors-try-1st-crispr-editing-in-the-body-for-blindness.html
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