Posted on 13 August 2020
Cannabidiol (), which can make up around 40% of the plant’s extract, is currently being investigated as a potential treatment for several medical conditions characterised by altered memory processing.
In this double-blind, randomised controlled trial, researchers used magnetic resonance imaging (MRI) to study the cerebral blood flow in 15 healthy individuals given a single dose of either oral or a placebo.
They found thatsignificantly increased blood flow to the , a region involved in memory processing and emotion, and to the , which is associated with planning and decision making.
did not significantly improve subjects’ memory performance. Greater blood flow to the cortex did correlate with shorter reaction time in a working memory task. However, as this study was in healthy subjects given a single dose, effects may differ in those with medical conditions receiving repeated doses. Rather, this research is significant because it reveals a mechanism by which CBD may treat multiple conditions.
To our knowledge, this is the first study to find that CBD increases blood flow to key regions involved in memory processing, particularly the hippocampus.
If replicated, these results could lead to further research across a range of conditions characterised by changes in how the brain processes memories, including Alzheimer’s disease, where there are defects in the control of blood flow, along with schizophrenia and post-traumatic stress disorder.Dr Michael Bloomfield (UCL Psychiatry), lead author
Cannabidiol Improves Blood Flow to Brain’s Hippocampus – Neuroscience News. (2020). Retrieved 13 August 2020, from https://neurosciencenews.com/cbd-hippocampus-16806/
The effects of acute cannabidiol on cerebral blood flow and its relationship to memory: An arterial spin labelling magnetic resonance imaging study: https://doi.org/10.1177/0269881120936419
Cannabidiol Improves Blood Flow to Brain’s Hippocampus: https://neurosciencenews.com/cbd-hippocampus-16806/